Registration Dossier
Registration Dossier
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EC number: 202-800-7 | CAS number: 99-91-2
Eye irritation
Administrative data
- Endpoint:
- eye irritation, other
- Type of information:
- other: The Merck Index
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- The Merck Index - Encyclopedia of Chemicals
- Year:
- 1 989
- Bibliographic source:
- The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989
Materials and methods
- Principles of method if other than guideline:
- not specified
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4'-chloroacetophenone
- EC Number:
- 202-800-7
- EC Name:
- 4'-chloroacetophenone
- Cas Number:
- 99-91-2
- Molecular formula:
- C8H7ClO
- IUPAC Name:
- 1-(4-chlorophenyl)ethan-1-one
- Test material form:
- not specified
Constituent 1
Results and discussion
In vitro
Results
- Irritation parameter:
- other: HIGHLY IRRITATING TO EYES, MUCOUS MEMBRANES
- Remarks:
- Entry in Merck Index: HIGHLY IRRITATING TO EYES
- Remarks on result:
- other: HIGHLY IRRITATING TO EYES, MUCOUS MEMBRANES
- Remarks:
- Entry in Merck Index: HIGHLY IRRITATING TO EYES
Applicant's summary and conclusion
- Interpretation of results:
- Category 2 (irritating to eyes) based on GHS criteria
- Conclusions:
- Entry in Merck Index: HIGHLY IRRITATING TO EYES, MUCOUS MEMBRANES leads to the classification Eye irrit 2, H319 and STOT SE 3, H335
- Executive summary:
Entry in Merck Index: HIGHLY IRRITATING TO EYES, MUCOUS MEMBRANES
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