Registration Dossier

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
not specified
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: information lacking, insufficient for assessment

Data source

Reference
Reference Type:
secondary source
Title:
ChemIDplus CAS 99-91-2
Bibliographic source:
"Manual of Pharmacology and Its Applications to Therapeutics and Toxicology," 8th ed., Sollman, T., Philadelphia, W.B. Saunders Co., 1957 Vol. 8, Pg. 192, 1957.

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4'-chloroacetophenone
EC Number:
202-800-7
EC Name:
4'-chloroacetophenone
Cas Number:
99-91-2
Molecular formula:
C8H7ClO
IUPAC Name:
4'-chloroacetophenone
Test material form:
not specified
Details on test material:
test material
Specific details on test material used for the study:
The respective test substance is not specified as to its chemical form.

Results and discussion

Applicant's summary and conclusion

Executive summary:

Test type: human TCLo

Route: Inhalation

Reported dose (normalized dose): 1mg/m3/1M (1mg/m3)

Effect: SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE