Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
reaction mass of: trisodium 3-(5-(2,6-difluoropyrimidin-4-ylamino)-2-sulfonatophenylazo)-5-(4-fluoro-6-morpholin-4-yl-1,3,5-triazin-2-ylamino)-4-hydroxy-2,7-naphthalenedisulfonate; trisodium 3-(5-(4,6-difluoropyrimidin-2-ylamino)-2-sulfonatophenylazo)-5-(4-fluoro-6-morpholin-4-yl-1,3,5-triazin-2-ylamino)-4-hydroxy-2,7-naphthalenedisulfonate
EC number: 436-890-6 | CAS number: -
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1998-04-24 to 1998-09-17
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Principles of method if other than guideline:
- Estimation of the log Pow from the saturation solubilities in n-octanol and water, as specified in Appendix 1 to EU method A.8 (Regulation (EC) No 440/2008).
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- -6.6
- Temp.:
- 20 °C
- Remarks on result:
- other: pH was not determined
- Details on results:
- The saturation concentration of Reactive Red FC 73270 in octanol was determined (by HPLC) to be 0.164 mg/L (mean value, n=2).
The saturation concentration of Reactive Red FC 73270 in water as reported by study EO 011-98 is 389,000 mg/L (i.e. 389 g/L).
Accordingly, the log Pow is calculated to be -6.6. - Conclusions:
- The n-octanol/water partition coefficient of Reactive Red FC 73270 as estimated from the solubilities in water and n-octanol is log Pow = -6.6.
- Executive summary:
A study was performed to determine the partition coefficient of Reactive Red FC 73270 from the saturated solubilities in n-octanol and water using the estimation method. The study was performed in accordance with EU method A.8 and in compliance with GLP.
The n-octanol/water partition coefficient of the test substance was determined to be log Pow = -6.6.
Reference
Description of key information
A study performed according to EU Method A.8. in compliance with GLP
examined the partition coefficient of the test substance using the HPLC method. The partition coefficient was found to be -6.6.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -6.6
- at the temperature of:
- 20 °C
Additional information
The n-octanol/water partition coefficient of the test substance Reactive Red FC 73270
estimated from solubility in water and n-octanol is log Pow = -6.6.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
