Registration Dossier

Physical & Chemical properties

Dissociation constant

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The dissociation constant was determined to be between 0.6 and 5.3 at 22°C in the acidic pH range.
No clear dissociation was observed in the alkaline range.

Key value for chemical safety assessment

Additional information

A study was performed to determine the dissociation constant of the test substance according to OECD guideline 112 and in compliance with GLP.

Dissociation was determined using spectrophotometric determination. The pKa determination was performed by adding test substance to hydrochloric acid or sodium hydroxide solution and measuring subsequently the pH and the UV-Vis spectra (200 to 800 nm) of each resulting solution.

The dissociation constant was determined to be between 0.6 and 5.3 at 22°C in the acidic pH range.

No clear dissociation was observed in the alkaline range.