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Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Description of key information

A study was performed according to OECD guideline 116 and in compliance with GLP. The fat solubility of the test substance was

less than 0.005 mg in 100 g fat at 37°C, i.e. below the detection limit of the lowest calibration standard.

Key value for chemical safety assessment

Solubility in mg/100g standard fat:
At the temperature of:
37 °C

Additional information

A study was performed to determine the fat solubility of the substance Reactive Red FC 73270. Mixtures of the test substance and fat were stirred for different times (3 or 27 h) and at different temperatures (30, 50 and 37 °C). The saturated liquid phase was separated from the undissolved test substance by filtration, mixed with hexane and extracted three times with water. The aqueous phases were combined and UV/Vis absorption spectra were recorded between 200 and 800 nm. The test substance showed fat solubility of < 0.005 mg in 100 g fat at 37 °C (i.e. below the detection limit).