Registration Dossier
Registration Dossier
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EC number: 200-798-2 | CAS number: 73-32-5
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Batch No. 140147K06B
- Expiration date of the batch: 2018-12-17
- Purity test date: 2015-02-18
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: ambient temperature (20+/-5°C), keep away from light and humidity. - Key result
- Percentile:
- D50
- Mean:
- 204.6 µm
- St. dev.:
- 1.77
- Remarks on result:
- other:
- Percentile:
- D10
- Mean:
- 39.5 µm
- St. dev.:
- 0.71
- Remarks on result:
- other:
- Remarks:
- mean of two measurements
- Percentile:
- D90
- Mean:
- 569.2 µm
- St. dev.:
- 12.37
- Remarks on result:
- other:
- Remarks:
- mean of two measurements
- Conclusions:
- The test item L-isoleucine has a median particle size D50 = 204.6 µm, which was determined by laser diffraction measurement.
- Executive summary:
The particle size distribution of L-isoleucine was determined by means of laser diffraction measurement in accordance with OECD and ISO guidelines and in line with GLP principles.
The test item was found to have a median particle size (D50) of 204.6 µm.
Reference
Test series 1:
D10: 38.5 µm
D50: 202.1 µm
D90: 551.7 µm
Test series 2:
D10: 39.5 µm
D50: 204.6 µm
D90: 569.2 µm
Description of key information
The particle size distribution of L-isoleucine was determined by means of laser diffraction measurement in accordance with OECD and ISO guidelines and in line with GLP principles. The test item was found to have a median particle size (D50) of 204.6 µm.
Additional information
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