Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 200-798-2 | CAS number: 73-32-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Flammability
Administrative data
Link to relevant study record(s)
- Endpoint:
- flammable solids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- according to guideline
- Guideline:
- other: UN-Brennbarkeitstests Klasse 4.1.
- Specific details on test material used for the study:
- No further details available.
- Key result
- Test procedure:
- burning rate test over 100 mm length
- Burning time:
- 46 s
- Remarks on result:
- other: average of two measurements
- Interpretation of results:
- not classified based on GHS criteria
- Conclusions:
- The test substance was determined to be readily combustible.
- Executive summary:
The burning rate of the test substance was determined via the propagation of combustion over a 100 mm long powder train. The average observed burning rate is 46s/100mm.
According to the criteria described in Regulation (EC) 1272/2008 on classification, labelling and packaging of substances and mixtures (CLP), classification as a flammable solid is required when the burning rate is more than 2.2 mm/s. This corresponds to a burning time of 45s/100mm or less. Based on an average observed burning rate of 46s/100 for L-isoleucine, classification of the substance as a flammable solid is not required.
Reference
The burning time was measured twice on a 100mm powder train.
Experiment 1: 48s
Experiment 2: 44s
Average burning rate: 46s/100mm.
Description of key information
The average observed burning rate for L-isoleucine is 46s/100mm.
Key value for chemical safety assessment
- Flammability:
- not classified
Additional information
The burning rate of the test substance was determined via the propagation of combustion over a 100 mm long powder train. The average observed burning rate is 46s/100mm.
Justification for classification or non-classification
According to the criteria described in Regulation (EC) 1272/2008 on classification, labelling and packaging of substances and mixtures (CLP), classification as a flammable solid is required when the burning rate is more than 2.2 mm/s. This corresponds to a burning time of 45s/100mm or less. Based on an average observed burning rate of 46s/100 for L-isoleucine, classification of the substance as a flammable solid is not required.
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