Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

L-isoleucine was determined to be readily biodegradable based on a BOD5/COD ratio of 1.6 (>> 0.5), and based on read-across from a recent GLP and OECD guideline study on L-valine.

Hydrolysis is not a relevant pathway due to the lack of hydrolysable groups.

Bioaccumulation of L-isoleucine can be excluded based on its low log Kow of -1.72.

Likewise, from this low log Kow value, a low tendency to bind to soil can be predicted.