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Diss Factsheets
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EC number: 701-079-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Based on the results of this study, the 72-hour and 96-hour EC50(algae) of ITC 288/S, based on biomass and on growth rate, was found to be > 100 mg/L. The 72-hour and 96-hour NOEC values, based on biomass and on growth rate, was found to be >= 100 mg/L.
Therefore, ITC 288/S should not be considered as harmful to the aquatic organisms tested.
Key value for chemical safety assessment
Additional information
The key stydy was performed on test material ITC 288/S on the growth of Selenastrum capricornutum (new name: Pseudokirchnerella subcapitata) according to the OECD Guidelines for Testing of Chemicals (1984) No. 201 and the US EPA Code of Federal Regulations Title 40, Part 797, Section 1050. The test was performed according to the GLP.
The test species were cultured under continuous illumination on an orbital shaker at 24°C for 96 hours, and were exposed to the test material at a nominal concentration of 100 mg/L under static test conditions. Growth was recorded after 24, 48, 72 and 96 hours by spectrophotometry. By comparison with control, the test substance showed no inhibition of the growth rate nor the biomass. Therefore, the effect concentrations were determined as follows:
72 -hr EbC50 > 100 mg/L
96 -hr EbC50 > 100 mg/L
72 -hr ErC50 > 100 mg/L
96 -hr ErC50 > 100 mg/L
72 -hr NOEC >= 100 mg/L based on biomass and growth rate
96 -hr NOEC >= 100 mg/L based on biomass and growth rate
Verification of test concentration showed that the concentrations were within the desired limits (i.e. >= 80% of nominal values) and therefore, the nominal test concentrations were used for the estimation of EC50 values.
The study has been performed in 1992. At that time, only one validity criteria was reported in the OECD TG 201, which requested that the cell density in the control cultures should have increased by a factor of at least 16 within three days. This validity criteria has been fulfilled as the biomass in the control cultures has increased by a factor of 99 and 180 within the 72-hour and 96-hour test periods respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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