Reaction products of tetrakis(hydroxymethyl)phosphonium chloride, urea and tetradecan-1-amine

Toxicity to aquatic algae and cyanobacteria

Description of key information

For the Proban STi (=THPC Urea Amine): 
EC50 = 1.25 mg/L
NOEC = 0.42 mg/L

Key value for chemical safety assessment

EC50 for freshwater algae:

1.25 mg/L

EC10 or NOEC for freshwater algae:

0.42 mg/L

Additional information

For the Proban STi, the results for the algae toxicity are :

EC₅₀ = 1.25 mg/L (expressed as notified substance)

NOEC = 0.42 mg/L (expressed as notified substance)

For the ITC826 Concentrate, the results for the algae toxicity are obtained below:

EC₅₀= 0.15 mg/L

NOEC = 0.037 mg/L

To be consistent with the UK competent authorities assessment (Notification number 97 -06 -0925), the results obtained with the most recent representative reaction product, Proban STi have to be considered in the risk assessment. Therefore, as the algae are also the most sensitive species, the EC50 of 1.25 is considered in the risk assessment for the PNEC derivation.