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Physical & Chemical properties

Partition coefficient

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Description of key information

The partition coefficient test has not been conducted because the substances in the lithium salts of monocarboxylic acids C14 -C22 category have high surface activity or do not dissolve in octanol or water. This is supported by partition coefficient studies which were attempted with lithium myristate, lithium 12-hydroxystearate and lithium behenate but were not feasible. As the tests could not be conducted on the substances with the longest and shortest carbon chain length in the category, as well as an intermediary substance, it is considered justified to expect that the remaining substances in the category with intervening carbon chain lengths would behave in the same manner and therefore cannot be tested for partition coefficient either.

Key value for chemical safety assessment

Additional information

GLP-compliant, guideline n-octanol water partition coefficient studies were attempted for lithium myristate, lithium 12 -hydroxystearate and lithium behenate but the studies were not feasible as the substances are either surface active or insufficiently soluble in octanol and water. QSAR estimates have been provided for representative structures covering the substances in the lithium salts of monocarboxylic acids C14 -C22 category, with Log Kow values ranging from 2.2 to 6.1. Further investigations on the partition coefficient of lithium 12 -hydroxystearate are currently ongoing (Covance 2020).