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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin sensitisation

Currently viewing:

Administrative data

Endpoint:
skin sensitisation: in vitro
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
See IUCLID section 13 for category and read across justification

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2020

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 442D (In Vitro Skin Sensitisation: ARE-Nrf2 Luciferase Test Method)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of study:
activation of keratinocytes

Test material

Constituent 1
Chemical structure
Reference substance name:
Lithium myristate
EC Number:
243-743-8
EC Name:
Lithium myristate
Cas Number:
20336-96-3
Molecular formula:
C14H28O2.Li
IUPAC Name:
lithium myristate
impurity 1
Chemical structure
Reference substance name:
Lithium laurate
EC Number:
238-663-5
EC Name:
Lithium laurate
Cas Number:
14622-13-0
Molecular formula:
C12H24O2.Li
IUPAC Name:
lithium laurate
impurity 2
Chemical structure
Reference substance name:
Lithium palmitate
EC Number:
243-842-6
EC Name:
Lithium palmitate
Cas Number:
20466-33-5
Molecular formula:
C16H32O2.Li
IUPAC Name:
lithium palmitate
impurity 3
Chemical structure
Reference substance name:
Lithium hydroxide
EC Number:
215-183-4
EC Name:
Lithium hydroxide
Cas Number:
1310-65-2
Molecular formula:
HLiO
IUPAC Name:
lithium hydroxide
Test material form:
solid
Details on test material:
- Batch number: A194-99/3
- Expiry date: 02 April 2022

Results and discussion

In vitro / in chemico

Results
Key result
Remarks on result:
other: Test currently ongoing
Remarks:
Test currently ongoing

Applicant's summary and conclusion

Interpretation of results:
other:
Remarks:
Test currently ongoing
Conclusions:
The skin sensitisation potential of lithium myristate was determined to be
Executive summary:

The skin sensitisation potential of lithium myristate in the in vitro OECD 442D Keratinosens test was determined to be