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Toxicological information

Repeated dose toxicity: oral

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Administrative data

Endpoint:
short-term repeated dose toxicity: oral
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
See IUCLID section 13 for category and read across justification

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2020

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 422 (Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Lithium myristate
EC Number:
243-743-8
EC Name:
Lithium myristate
Cas Number:
20336-96-3
Molecular formula:
C14H28O2.Li
IUPAC Name:
lithium myristate
Test material form:
other: Solid salt prepared in situ in medicinal white oil for dosing
Details on test material:
- Form of test item: Prepared in situ
- Vehicle: Medicinal White Oil
- Concentration in vehicle: X % w/w

Test animals

Species:
rat

Results and discussion

Effect levels

Remarks on result:
other: Test ongoing

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
The short-term repeat dose toxicity of lithium myristate was determined to be
Executive summary:

The short-term repeat dose toxicity of lithium myristate to rats was determined in a GLP-compliant study following OECD guideline 422.