4H-1,2,4-Triazole, 4-[[bis(4-fluorophenyl)methylsilyl]methyl]-

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: No analytical monitoring

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1988

Report date:

1988

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)

Deviations:

no

Remarks:

The study was conducted according to guideline in effect at time of study conduct.

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

bis(4-fluorophenyl)methyl(4H-1,2,4-triazol-4yl-methyl)silane

EC Number:

600-198-4

Cas Number:

101377-47-3

Molecular formula:

C16H15N3F2Si

IUPAC Name:

bis(4-fluorophenyl)methyl(4H-1,2,4-triazol-4yl-methyl)silane

Details on test material:

- Purity: R7623 Technical, solid

Sampling and analysis

Analytical monitoring:

no

Test solutions

Vehicle:

yes

Test organisms

Test organisms (species):

Daphnia magna

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

24 h

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

24 h

Dose descriptor:

EC50

Effect conc.:

20.5 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Effect concentrations 2

Duration:

24 h

Dose descriptor:

NOEC

Effect conc.:

10 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Any other information on results incl. tables

Lowest concentration producing 100% mortality was 32 mg/L.

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

24-hour EC50 = 20.5 mg/L
24-hour NOEC = 10 mg/L

Executive summary:

An acute, static 24-hour test was conducted at nominal concentrations of 0, 10, 18, 32, 56 and 100 mg/L on Daphnia magna. Exposure after 24 hours resulted in 100% immobility at 32 mg/L. Based on nominal concentration , the EC50 was 20.5 mg/L and the NOEC was 10 mg/L.