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Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1988
Report date:
1988

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
Deviations:
no
Remarks:
The study was conducted according to the test guidelines in effect at the time of study conduct.
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
bis(4-fluorophenyl)methyl(4H-1,2,4-triazol-4yl-methyl)silane
EC Number:
600-198-4
Cas Number:
101377-47-3
Molecular formula:
C16H15N3F2Si
IUPAC Name:
bis(4-fluorophenyl)methyl(4H-1,2,4-triazol-4yl-methyl)silane
Details on test material:
- Purity: R7623 Technical, solid

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
standard fat
Solubility:
3.66 other: g/kg
Temp.:
37 °C
Remarks on result:
other: value for R7623 Technical
Medium:
standard fat
Solubility:
2.78 other: g/kg
Temp.:
37 °C
Remarks on result:
other: value for R7623
Medium:
standard fat
Solubility:
>= 10.65 other: g/kg
Temp.:
37 °C
Remarks on result:
other: value for H6573
Test substance stable:
yes

Applicant's summary and conclusion

Conclusions:
value for R7623 Technical = 3.66 g/kg
value for R7623 = 2.78 g/kg
value for H6573 ≥ 10.65 g/kg
Executive summary:

The solubility of R7623 Technical in standard fat was determined to be 3.66 g/kg at 37 °C. The fat solubilities of the individual components of R7623 Technical were determined to be 2.78 g/kg and ≥ 10.65 g/kg for R7623 and H6573, respectively, at 37 °C.