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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

EC50(48h) > 980 mg/L for Daphnia magna (OECD 202)

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
980 mg/L

Additional information

There is one short-term aquatic invertebrate study available for 2-amino-2-(hydroxymethyl)-1,3-propanediol (TRIS AMINO), which was used as key study for the assessment. The study was conducted according the OECD guideline 202 and GLP (Urann, 2011). The test organism Daphnia magna was exposed to TRIS AMINO in a static system for 48 hours, at the measured test concentrations 63, 130, 260, 520, 980 mg a.i./L. Except for a 15% immobilisation at the highest test concentration, no effects were observed. The EC50 value was thus estimated to be > 980 mg/L.