Tris(2-hydroxyethyl)-1,3,5-triazinetrione

Short-term toxicity to aquatic invertebrates

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Guideline study under GLP

Remarks:

(as given in OECD SIDS)

Qualifier:

according to guideline

Guideline:

OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)

GLP compliance:

yes

Analytical monitoring:

yes

Test organisms (species):

Daphnia magna

Test type:

static

Key result

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

> 1 000 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

- Measured concentration (as mg/L): <1 for control, 930 for the test solution at the beginning of the test; <1 for control, 930 for the test solution at end of the test.
- Statistical results: Not described
- Biological observations 

 Number immobilized as compared to the number exposed: 

Nominal concentration (mg/L)	Measured concentration (mg/L)	Cumulative numbers of immobilized Daphnia (Percent immobility)
		24 h	48 h
Control	-	0 (0)	0 (0)
1000	930 a	0 (0)	0 (0)

 a: geometric mean

Concentration response with 95 % confidence limits: Not described
Cumulative immobilisation: 0 % immobility in control and 1,000 mg/L
Was control response satisfactory (yes/no/unknown): Yes
Reference substance results: 48h-EC50 of potassium bichromate: 0.57 mg/L

 

Conclusions:

There was no inhibition of immobilisation and no abnormal response during the exposure, and 48h-EC50 was greater than 1,000 mg/L of the concentration used.

Description of key information

EC50 (48h) >1000 mg/L for Daphnia magna (OECD TG 202)

Additional information

Value used for CSA: EC50/LC50 for freshwater invertebrates: >1000 mg/L