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Physical & Chemical properties

Melting point / freezing point

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Endpoint:
melting point/freezing point
Type of information:
other: Literature
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
As referenced in REACH Guidance Document 7a pg 28, “The use of Klimisch codes (Klimisch et al., 1997), can be extended to these secondary sources and a reliability code of (2) valid with restrictions should be assigned when using an authoritative secondary source.”
Deviations:
not specified
Remarks:
Guideline used not reported
Principles of method if other than guideline:
No details are provided in the reference concerning the method employed.
GLP compliance:
not specified
Melting / freezing pt.:
>= 35 - <= 38 °C
Conclusions:
35 to 38 degrees Celsius
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
As referenced in REACH Guidance Document 7a pg 29, “The use of Klimisch codes (Klimisch et al., 1997), can be extended to these secondary sources and a reliability code of (2) valid with restrictions should be assigned when using an authoritative secondary source.”
Deviations:
not specified
Remarks:
The guideline was not stated.
Principles of method if other than guideline:
No details are provided in the reference concerning the method employed.
GLP compliance:
not specified
Melting / freezing pt.:
37 °C
Conclusions:
37 deg Celsius
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
As referenced in REACH Guidance Document 7a pg 29, “The use of Klimisch codes (Klimisch et al., 1997), can be extended to these secondary sources and a reliability code of (2) valid with restrictions should be assigned when using an authoritative secondary source.”
Deviations:
not specified
Remarks:
No guideline is reported.
Principles of method if other than guideline:
No details are provided in the reference concerning the method employed.
GLP compliance:
not specified
Melting / freezing pt.:
312.15 K
Endpoint:
melting point/freezing point
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Deviations:
not applicable
Principles of method if other than guideline:
No details are provided in the reference concerning the method employed.
GLP compliance:
not specified
Type of method:
other: QSAR
Melting / freezing pt.:
37 °C
Remarks on result:
other: Experimental database

Description of key information

Based on information from several literature sources the melting point ranges from 35 -39°C. The mean value of 37°C was used for risk assessment.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
37 °C

Additional information