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EC number: 204-884-0 | CAS number: 128-39-2
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- other: Literature
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- As referenced in REACH Guidance Document 7a pg 28, “The use of Klimisch codes (Klimisch et al., 1997), can be extended to these secondary sources and a reliability code of (2) valid with restrictions should be assigned when using an authoritative secondary source.”
- Deviations:
- not specified
- Remarks:
- Guideline used not reported
- Principles of method if other than guideline:
- No details are provided in the reference concerning the method employed.
- GLP compliance:
- not specified
- Melting / freezing pt.:
- >= 35 - <= 38 °C
- Conclusions:
- 35 to 38 degrees Celsius
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- As referenced in REACH Guidance Document 7a pg 29, “The use of Klimisch codes (Klimisch et al., 1997), can be extended to these secondary sources and a reliability code of (2) valid with restrictions should be assigned when using an authoritative secondary source.”
- Deviations:
- not specified
- Remarks:
- The guideline was not stated.
- Principles of method if other than guideline:
- No details are provided in the reference concerning the method employed.
- GLP compliance:
- not specified
- Melting / freezing pt.:
- 37 °C
- Conclusions:
- 37 deg Celsius
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- As referenced in REACH Guidance Document 7a pg 29, “The use of Klimisch codes (Klimisch et al., 1997), can be extended to these secondary sources and a reliability code of (2) valid with restrictions should be assigned when using an authoritative secondary source.”
- Deviations:
- not specified
- Remarks:
- No guideline is reported.
- Principles of method if other than guideline:
- No details are provided in the reference concerning the method employed.
- GLP compliance:
- not specified
- Melting / freezing pt.:
- 312.15 K
- Endpoint:
- melting point/freezing point
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Deviations:
- not applicable
- Principles of method if other than guideline:
- No details are provided in the reference concerning the method employed.
- GLP compliance:
- not specified
- Type of method:
- other: QSAR
- Melting / freezing pt.:
- 37 °C
- Remarks on result:
- other: Experimental database
Referenceopen allclose all
Description of key information
Based on information from several literature sources the melting point ranges from 35 -39°C. The mean value of 37°C was used for risk assessment.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 37 °C
Additional information
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