Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-884-0 | CAS number: 128-39-2
Endpoint summary
Administrative data
Description of key information
The most sensitive endoints were:
short-term: 48h-Daphnia magna EC50: 0.45 mg/L
long-term: 21d-Daphnia magna NOEC: 0.035 mg/L
Additional information
The environmental hazard assessment for (fresh-) water organisms and sediment habitats is supported by several acute studies (pelagic compartment), a chronic Daphnia reproduction study, NOEC values for algal tests and by using scientific argumentation (sediment dwelling organisms).
For the environmental hazard assessment of 2,6-DTBP acute toxicity studies for freshwater fish, invertebrates (Daphnia magna and Gammarus fasciatus), freshwater algae and STP microorganisms are available. In addition, a long-term Daphnia reproduction study and 96h-NOEC data from algae studies is available. A long-term study for fish is waived since a long-term study is available for the more sensitive group, e.g., the daphinds. Experimental information about toxicity on marine organisms is not available.
The short-term EC50/LC50 values for fish, Daphnia, algae and microorganisms were 1.4, 0.45, 1.2 and > 1000 mg 2,6 DTBP/L, respectively. In addition, a 96h-test with the sediment dweller Gammarus fasciatus is available resulting in a 96h-EC50 of 0.6 mg/L. Gammarus fasciatus is less sensitive than Daphnia magna.
The daphnids (Daphnia magna) were the most sensitive trophic level/species in short-term tests having an EC50 of 0.45 mg/L. Consequently, this species was used also for chronic testing. The long-term test with Daphnia magna resulted in a 21 day-NOEC (mortality, reproduction, growth) of 0.035 mg/L. This value of 0.035 mg/L will be used for the risk assessment of aquatic organisms.
2,6-DTBP has a log Pow of < 5, and the calculation of the PEC/PNEC ratios using the EPM resulted in values < 1. Consequently sediment toxicity tests do not need to be conducted. This is supported by the finding that In an acute 96h-study Gammarus fasciatus is less sensitive when compared to Daphnia magna.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
