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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

NOEC (3 h): ≥ 1000 mg/L for activated sludge microorganisms (OECD 209)

Key value for chemical safety assessment

Additional information

One experimental study investigating the inhibition of the respiration of Reaction mixture of Glycerol 1,3- di(acetate), glycerol acetate and triacetin to activated sludge microorganisms is available (Roulstone, 2012). The study was conducted according to OECD 209 under GLP conditions using activated sludge from a sewage treatment plant treating predominantly domestic sewage. Three concentrations (10, 100 and 1000 mg/L) were tested in a range-finding test. No inhibition of respiration rate was measured after 3 h contact time resulting in a NOEC of ≥ 1000 mg/L. An increase of the respiration rate was measured instead in all treatments. Thus, it is considered justifiable that the range-finding study is sufficient and no definitive study is necessary. Reaction mixture of Glycerol 1,3- di(acetate), glycerol acetate and triacetin is not expected to exhibit effects on the microorganism community in sewage treatment plants and inhibition of the subsequent degradation process is not expected.