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Diss Factsheets
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EC number: 204-825-9 | CAS number: 127-18-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The lowest valid 48-h EC50 is 8.5 mg/l for the freshwater Daphnia magna tested under static conditions.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 8.5 mg/L
Additional information
Various tests have been carried out to study the toxicity of tetrachloroethylene to invertebrates of which the outcomes are in the same order of magnitude. Studies were evaluated as reliable when measures were taken to monitor concentrations and/or to minimise evaporation of tetrachloroethylene from the test solutions.
For freshwater toxicity the lowest 48-h EC50 reported for Daphnia magna is 8.5 mg/l (Richter et al., 1983) and is based on measured concentrations. The test conditions are fully described for this result and the test is therefore considered valid. A 24-h EC50 of 3.2 mg/l is reported by Bazin et al. (1987) based upon nominal concentrations. No details are given as to the test method used, therefore this study is considered not valid. For other freshwater invertebrates a 3-h EC50 of 1.8 mg/l is reported for Monia macrocopa (Yoshioka et al., 1986). This result is based upon nominal concentrations; the test methods used are also poorly described and therefore considered not valid. For the marine compartment a study with Americamysis bahia (tested as Mysidopsis bahia) is available (USEPA, 1980), little indication is given as to the test conditions and the results can therefore not be used in the assessment. The reported 96-h LC50 is 10.2 mg/l. For Elminius modestus a 48-h EC50 of 3.5 mg/l is reported (Pearson and McConnell, 1975). This result is based upon nominal concentrations; the test methods used are also poorly described and therefore considered not valid. Other studies were less critical and/or not reliable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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