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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

72 hour EC50, growth rate, Desdemodesmus subspicatus: 1058 mg/L

72 hour EC20, growth rate, Desdemodesmus subspicatus: 508 mg/L

72 hour EC10, growth rate, Desdemodesmus subspicatus: 346 mg/L

72 hour NOEC, growth rate, Desdemodesmus subspicatus: 125 mg/L

Key value for chemical safety assessment

EC50 for freshwater algae:
1 058 mg/L
EC10 or NOEC for freshwater algae:
125 mg/L

Additional information

The 1,4 -butynediol 72 hour NOEC for growth rate of the freshwater alga (Desdemodesmus subspicatus) provided in a DIN 38412 guideline study is 125 mg/L, the 72 hour EC10 is 346 mg/L, and the 72 hour EC50 is 1058 mg/L (BASF AG 1988). These data are supported by the results of a guideline-equivalent study with Scenedesmus subspicatus which yielded a 72 hour IC50 of >100 mg/L (Tisler, et. al., 2003).