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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Lethal Concentration 0% (LC0): 21.5 mg/L

Lethal Concentration 50% (LC50): 76.1 mg/L

Lethal Concentration 100% (LC100): 100 mg/L

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
76.1 mg/L

Additional information

The acute toxicity of 1,4 -Butynediol (B3D) to freshwater fish has been tested according to various guideline and non-guideline methods under non-GLP conditions. Tests results with Klimisch scores of at least 2 yielded 96 hr LC50 values of 53.6 mg/L (Veith, et. al., 1989) to 76.1 mg/L (Tisler, et. al., 2003), and a 96 hr NOEC of 21.5 mg/L and LC100 of 100 mg/L (BASF AG, 1988). These data indicate that 1,4 -Butynediol is moderately toxic to freshwater fish.