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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Repeated dose toxicity: other routes

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Administrative data

Endpoint:
chronic toxicity: other route
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
Experimental derivation of maximum permissible concentrations of isophthaloyl chloride in water reservoirs
Author:
Devyatka DG, Stepanyuk GL, Pushkar MS, Makats VG, Rybak PG, Vashchuk AA, Govachuk GP, and Korolik AG
Year:
1982
Bibliographic source:
Gig. Sanit., (7):75-78 (CA97:121516j)

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Isophthaloyl dichloride
EC Number:
202-774-7
EC Name:
Isophthaloyl dichloride
Cas Number:
99-63-8
Molecular formula:
C8H4Cl2O2
IUPAC Name:
benzene-1,3-dicarbonyl dichloride
Details on test material:
Isophthaloyl chloride, purity not reported

Results and discussion

Results of examinations

Details on results:
Chronic experiments showed that the minimum acting dose was 2.36 mg/kg and maximum nonacting dose was 1.18 mg/kg.

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion