Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

biotransformation and kinetics
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
supporting study
Study period:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Abstract from Symposium

Data source

Reference Type:
review article or handbook
Higher alcohols bioconcentration: Influence of Biotransformation
Watze De Wolf and Tom Parkerton
Bibliographic source:
217th ACS National Meeting, Anaheim,CA Symposium 'Persistent, Bioaccumulative, Toxic Chemicals'

Materials and methods

Test guideline
equivalent or similar to guideline
Principles of method if other than guideline:
Made use of OECD 305 guideline
GLP compliance:
Stated in the abstract
Type of medium:

Test material

Constituent 1
Reference substance name:
Commercial branched chain alcohols of 10, 12 and 13 carbon atoms
Commercial branched chain alcohols of 10, 12 and 13 carbon atoms

Results and discussion

Any other information on results incl. tables

Water analysis showed that exposure concentrations were maintained relatively constant during the uptake phase. The uptake phase showed the fish attained rapid and steady state concentration of the alcohol. Rapid elimination occured after transfer to clean water. Measurement of the BCF values at the lower water concentration tested were 16, 29 and 30 for C10 , C12 and C13 -alcohol. Measured BCF values were dependant on water concentration with a two-fold increase observed for the C12 and C13 alcohol.

Applicant's summary and conclusion

There is no specific conclusion on the bioconcentration factor in fish for Isoundecanol.
Executive summary:

The results of bioconcentration testing in fish clearly showed lack of any substantial bioconcentration of the C10, C12 and C13 alcohols tested. The BCF value were 16, 29 and 30 , respectively. Isoundecanol (C11) is closely related to this group of alcohols, and although the information is taken from a scientific abstract, it is considered adequate to support the non PBT status of Isoundecanol.