Registration Dossier

Environmental fate & pathways


Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

C12-C18 TMAC is considered to be hydrolytically stable.

Key value for chemical safety assessment

Additional information

A guideline study was conducted to evaluate the hydrolysis rate of C12-C18 TMAC as a function of pH. The study was conducted under dark conditions using three buffer solutions and one unbuffered solution (pH of approximately 6.2) at 25±1˚C: pH 5 [acetic acid/sodium acetate], pH 7 [tris(hydroxymethyl) - amino methane/HCl], pH 9 [boric acid/sodium borate], and a solution containing deionized water. The buffer solutions were spiked at approximately 100 ppm levels (based on 100% activity of the test substance). Each of the four solutions was sampled on Day 0, 5, 12, 19, 26 and 33 of the study. The pH of each solution remained within 0.1 pH unit of the starting value throughout the 33-day sampling period. Each buffer solution was analysed in duplicate. Under the conditions of the study, the test substance was considered to be hydrolytically stable. More than 90% of the test substance remained intact at all aqueous pH systems over a 30-day period (Szajer G, 1989).