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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15 June 2012
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Remarks:
Water solubility as critical micelle concentration (CMC)
Principles of method if other than guideline:
For surface active substances the critical micelle concentration (CMC) method is used as an alternative to the water solubility. The critical micelle concentration (CMC) is determined by measuring the surface tension of test substance solutions at different test substance concentration. For surface active substances which form micelles in solution, the surface tension decreases with increasing concentration until the CMC is reached. At concentrations above the CMC, the surface tension remains constant. The CMC is determined from a plot of the surface tension versus the logarithm of the test substance concentration.

GLP compliance:
not specified
Type of method:
other: critical micelle concentration (CMC)
Key result
Water solubility:
ca. 0.73 g/L
Conc. based on:
test mat.
Temp.:
21.31 °C
Remarks on result:
other: critical micelle concentration (CMC)
Conclusions:
Under the study conditions, the water solubility (critical micelle concentration) of the test substance was determined to be 0.73 g/L at 21.31°C.

Executive summary:

A study was conducted to determine the water solubility of the test substance, C12-18 TMAC (100% active) using the critical micelle concentration (CMC) method, which is recommended for surface active substances. Under the study conditions, the CMC of the test substance was determined to be 0.73 g/L at 21.31°C (Mangnus, 2019).

Description of key information

The water solubility of the test substance was determined using critical micelle concentration (CMC) method, which is recommended for surface active substances (Mangnus, 2019).

Key value for chemical safety assessment

Water solubility:
0.73 g/L
at the temperature of:
21.31 °C

Additional information

(moderate water solubility)