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EC number: 800-309-8 | CAS number: 231297-75-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012-09-20 - 2012-12-19
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study with certificated GLP compliance. No methodology deficiencies are reported.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- The Department of Health of the Government of The United Kingdom
- Type of method:
- flask method
- Water solubility:
- 0 g/L
- Temp.:
- 20
- Remarks on result:
- other: pH is not reported.
- Details on results:
- Anionic components must have been present since an anion exchange column was required. Based on this components, the determined water solubility was an over estimation since the anions have the typical structure of a surface active material and it could be different to remove the excess from the samples. Additionally, the water solubility of the test substance in an undissociated from would be expected to be much lower than the obtained result.
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The study report describes a valid guideline study conducted under certificated GLP compliance. The water solubility was determined to be 1.98 x 10E-4 g/L at 20 +/- 0.5 °C. - Executive summary:
Using the shake flask method, the water solubility of magnesium sulfonate target substance (CAS 231297-75-9) was determined according to OECD Guideline 105/EU Method A.6 (Fox, 2012). A preliminary test was performed in order to select the appropriate method (column elution or shake flask) and to determine the approximate amount of test substance to be used in the definitive test. The sample analysis was performed via High Performance Liquid Chromatography (HPLC). As result, a water solubility of 1.98 x E-4 g/L at 20 +/- 0.5 °C is reported. Anionic components must have been present since an anion exchange column was required. Based on this components, the determined water solubility was an over estimation since the anions have the typical structure of a surface active material and it could be different to remove the excess from the samples. Additionally, the water solubility of the test substance in an undissociated from would be expected to be much lower than the obtained result.
Reference
Table 1. Mean Peak Areas
Solution |
Mean Peak Area |
Standard 103mg/L |
4.4879x107 |
Standard 106mg/L |
4.7949x107 |
Sample 1A |
1.5136x107 |
Sample 1B |
1.0362x107 |
Sample 2A |
6.1113x106 |
Sample 2B |
3.7221x106 |
Sample 3A |
7.8210x106 |
Sample 3B |
9.5757x106 |
Table 2. Test substance concentration in sample solutions
Sample Number |
Time Shaken at ~ 30 °C (hours) |
Time Equilibrated at20°C (hours) |
Concentration (g/L) |
Solution pH |
1 |
24 |
24 |
2.88 x 10-4 |
6.0 |
2 |
48 |
24 |
1.11 x 10-4 |
6.0 |
3 |
72 |
24 |
1.96 x 10-4 |
6.1 |
Description of key information
OECD 105/EU Method A.6_Shake flask method_Water solubility: 0.198 mg/L
Key value for chemical safety assessment
- Water solubility:
- 0.198 mg/L
- at the temperature of:
- 20 °C
Additional information
The key value was determined using the shake flask method in accordance to OECD Guideline 105/EU Method A.6 (Fox, 2013). The test substance is considered to be slightly soluble at 20 +/- 0.5 °C.
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