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Short-term toxicity to aquatic invertebrates

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Description of key information

No toxicity observed even at highest concentration level tested.
RA_CAS71786-47-5_OECD 202_Daphnia magna: EL50 (48h) > 1000 mg/L WAF
RA_CAS115733-09-0_OECD 202_Daphnia magna: EC50 (48h) > 1000 mg/L WAF

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
1 000 mg/L

Additional information

General considerations

The acute toxicity to aquatic invertebrates was investigated for different analogues structures of the magnesium sulfonate target substance (CAS 231297-75-9). For the substance itself, no experimental data are available. Since all substances used belong to the same chemical group, aryl-alkyl sulfonates, the same behaviour and toxicity potential can be expected. The following read-across substances were used to fulfil the endpoint of short-term toxicity to Daphnia magna: Magnesium read-across substance (CAS 71786 -47 -5) and calcium read-across substance (CAS 115733-09-0). Investigations concerning toxicity in marine invertebrates were not performed. For the detailed procedure of the read-across principle and justifications, please refer to the separate Read-Across Statement attached to this Chemical Safety Report.

Acute toxicity to freshwater invertebrates

All available experiments were conducted in accordance to OECD Guideline 202 and under GLP compliance. Based on the intrinsic properties of the used substances, Water Accommodated Fractions (WAFs) were prepared for testing. Daphnia magna was exposed to the test substance for a duration of 48 h, whereby mortality, immobilisation as well as sublethal effects were recorded daily.

The toxicity of the magnesium sulfonate read-across substance (CAS 71786-47-5) under static conditions was investigated by Ward (1993). Daphnids were exposed to control and test chemical at nominal concentrations of 100, 300 and 1000 mg/L WAF for 48 hours. No immobilisation of daphnids was recorded in the control and all the treatment groups. Therefore, the EL50 (48h) is reported to be > 1000 mg/L.

The calcium read-across substance (CAS 115733-09-0) was investigated with nominal concentrations of 100, 300 and 1000 mg/L WAF (Ward, 1993). After 24 h, no immobilised or dead organisms were observed. At the end of the experiment, 5 %, 0 %, 20 % and 5 % immobilisation were reported for the control, 100, 300 and 1000 mg/L WAF, respectively. Therefore, the test substance is considered as non-toxic to daphnids at WAF loading rates up to 1000 mg/L. The EC50 (48h) is > 1000 mg/L WAF.

Conclusion:

No toxic effects observed in both acute studies with daphnids even at the highest concentration levels tested.