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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012-11-30 - 2012-12-05
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
GLP compliance:
yes (incl. certificate)
Remarks:
The Department of Health of the Government of The United Kingdom
Type of method:
effusion method: vapour pressure balance
Temp.:
25 °C
Vapour pressure:
0.01 Pa
Temp.:
99 °C
Vapour pressure:
0.457 Pa

The test substance did not change in appearance under the conditions used in the determination.

Table 1. Vapour pressure data at 25 °C

Run

Log10[Vp (25 ºC)]

2

-2.07

3

-1.85

4

-1.86

5

-1.96

6

-1.89

7

-2.07

8

-2.01

9

-2.06

10

-2.10

Mean

-1.99

Vapor Pressure

1.03 x 10-2Pa

Table 2. Vapour pressure at 99 °C

Run

Log10[Vp(99 ºC)]

2

-0.154

3

-0.244

4

-0.287

5

-0.324

6

-0.365

7

-0.381

8

-0.419

9

-0.436

10

-0.454

Mean

-0.340

Vapor Pressure

0.457 Pa

Conclusions:
The study report describes a valid guideline study conducted under certificated GLP compliance. The vapour pressure was determined as 0.01 Pa at 25 °C and 0.457 Pa at 99 °C.
Executive summary:

The vapour pressure of magnesium sulfonate target substance (CAS 231297-75-9) was determined using the effusion method (vapour pressure balance) according to OECD Guideline 104 / EU Method A.4 (Tremain, 2012). The Temperature was controlled electronically. Using the cross-section, a diagram ws drawn and the system was evacuated. Afterwards the shutter was opened above the sample oven, which directed the escaping vapour jet towards the scale pan. The difference in mass reading the orifice covered and uncovered is proportional to the vapor pressure at the given oven temperature. A preliminary run was undertaken over the temperature range 20 °C to 114 °C in order to provide information for a suitable temperature range for the main test. A final sequence of ten runs was started after a sample of test substance had been under vacuum for approximately 69 1/4 hours. Temperature and pressure readings were taken between 90 and 100 °C with a one hour dwell at 90 °C between runs. As result, the vapour pressure at 25 °C was determined as 0.01 Pa and at 99 °C the value is given as 0.457 Pa, respectively.

Description of key information

OECD 104 / EU Method A.4_vapour pressure balance_effusion method_vapour pressure: 0.01 Pa at 25 °C; 0.457 Pa at 99 °C

Key value for chemical safety assessment

Vapour pressure:
0.01 Pa
at the temperature of:
25 °C

Additional information

The key value was determined using the vapour pressure balance (effusion method) in accordance to OECD Guideline 104/EU Method A.4 (Tremain, 2013).