Registration Dossier
Registration Dossier
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EC number: 205-232-8 | CAS number: 136-23-2
Endpoint summary
Administrative data
Description of key information
Additional information
In the assessment a 96-h LC50 value of > 16 mg/L is used from a non-GLP, OECD 203 guideline study with the guppy Poecilia reticulata conducted under semi-static conditions without analytical monitoring (Akzo Nobel Research Laboratories, 1991).
One short-term toxicity study with Daphnia magna is available for zinc bis(dibutyldithiocarbamate). The test is a static GLP-compliant, EPA-660/3-75-009 guideline study without analytical monitoring (Analytical Bio-Chemistry Laboratories, Inc., 1983c). The 48-h LC50 value of 0.74 mg/L is used in the assessment.
No growth inhibition tests with algae are available for zinc bis(dibutyldithiocarbamate). The results from the structural analogue zinc diethyldithiocarbamate are used (for details see Reporting Format as attached to the respective IUCLID entry and CSR Appendix A.1). A 96-h ErC50 value of 1.1 mg/L in Chlorella pyrenoidosa from a semi-static non-GLP, OECD 202 guideline study without analytical monitoring (van Leeuwen et al., 1985b; van Leeuwen, 1986) is used in the assessment.
A 10-d NOEC value of 320 µg/L in Danio rerio (tested as Brachydanio rerio) from a non-GLP, OECD 204 guideline study with the guppy conducted under semi-static conditions without analytical monitoring (Akzo Nobel Research Laboratories, 1991) is used in the assessment.
No long-term tests are available with Daphnia for zinc bis(dibutyldithiocarbamate). The results from the structural analogue zinc bis(diethyldithiocarbamate) are used (for details see Reporting Format as attached to the respective IUCLID entry and CSR Appendix A.1). A 21-d NOEC value of 3.2 µg/L in Daphnia magna from a semi-static non-GLP, near guideline study without analytical monitoring (van Leeuwen et al., 1985a; 1986) is used in the assessment.
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