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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

No well-documented data are available for chronic toxicity of cetrimonium bromide to fish.

Key value for chemical safety assessment

Additional information

Study is scientifically unjustified and disregarded based on the following:

1. In the aquatic environment cetrimonium bromide is expected to strongly adsorb to particles.

2. When present in low concentrations in the water phase cetrimonium bromide is expected to be biodegraded.

3. Cetrimonium bromide has a low bioaccumulation

4. Crustaceans and algae are more sensitive organisms to cetrimonium bromide than fish. Chronic toxicity to crustaceans is therefore more representative for long term effects of cetrimonium bromide in the aquatic environment. Reference is made to unpublished data reporting a chronic NOEC for fish for the substance dodecyltrimethylammonium chloride of 0.46 mg/L . No details were given so the value can only be used as an indication of the level of chronic toxicity for cetrimonium bromide to fish to be below the mg/L range.