Registration Dossier
Registration Dossier
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EC number: 200-311-3 | CAS number: 57-09-0
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No well-documented data are available for chronic toxicity of cetrimonium bromide to fish.
Key value for chemical safety assessment
Additional information
Study is scientifically unjustified and disregarded based on the following:
1. In the aquatic environment cetrimonium bromide is expected to strongly adsorb to particles.2. When present in low concentrations in the water phase cetrimonium bromide is expected to be biodegraded.
3. Cetrimonium bromide has a low bioaccumulation
4. Crustaceans and algae are more sensitive organisms to cetrimonium bromide than fish. Chronic toxicity to crustaceans is therefore more representative for long term effects of cetrimonium bromide in the aquatic environment. Reference is made to unpublished data reporting a chronic NOEC for fish for the substance dodecyltrimethylammonium chloride of 0.46 mg/L . No details were given so the value can only be used as an indication of the level of chronic toxicity for cetrimonium bromide to fish to be below the mg/L range.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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