Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

One study has examined the oral absorption, distribution and excretion of cetrimonium bromide.

One study has examined the percutaneous absorption of dodecyltrimethylammonium bromide in rats, in vivo

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential
Absorption rate - oral (%):
Absorption rate - dermal (%):
Absorption rate - inhalation (%):

Additional information

From a toxicokinetic study with oral gavage administration of radioactive cetrimonium bromide to rats, an oral absorption rate of 3 - 9% (average 6%) has been estimated. Radioactivity in tissues declined rapidly and no bioccumulation in tissues could be expected.

From dermal exposure of rats to radioactive dodecyltrimethylammonium bromide, the percutaneous absorption of the applied radioactivity was 3.15% corresponding to 28.4 ug/cm2.

Absorption rate - inhalation is 100% as default.