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Vapour pressure

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Description of key information

Key value for chemical safety assessment

Vapour pressure:
0.04 Pa
at the temperature of:
20 °C

Additional information

In the non-GLP Klimisch 2 key study from Kintrup, the vapour pressure of the test item Butanedioic acid, 2(or 3)-sulfo-, 4-[2-[(1-oxo(C12-18(even numbered) and C18 unsaturated)alkyl)amino]ethyl]esters, disodium salts was calculated. An estimation procedure in accordance with the test method OECD Guideline 104 “OECD Guideline For The Testing Of Chemicals, adopted by the Council on 23 March 2006, Vapour Pressure” ANNEX Estimation Method newest version (Robert S. Boethling, Donald Mackay, Handbook of Property Estimation Methods for Chemicals, Lewis Publishers, year of publication 2000, Cap. 3 - Vapour Pressure, Grain-Watson Method, p. 53 – 65) was used. This method is applied for vapour pressures between 10^3 to 10^-7 mbar. This deviates from the older version published in OECD Guideline 104. It was used due to the differentiation between solids and liquids, which results in a more precise estimate.

Using a melting point of 219 °C and a boiling point of 238°C (both values might be underestimations due to decomposition) resulted in a finding that the test item has a vapour pressure of ≤ 4.0*10-2Pa (≤ 4.0*10-4mbar) at 20 °C according to the definition in the OECD Guideline 104 (Grain-Watson estimation).

This value is considered reliable for the further risk assessment.