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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
19 mg/L

Additional information

In the Klimisch 1 GLP study from Kimmel (2013) the acute toxicity of item Butanedioic acid, 2(or 3)-sulfo-, 4-[2-[(1-oxo(C12-C18(even numbered) and C18unsaturated)alkyl))amino]ethyl]esters, disodium salts on Daphnia magna was determined in an 48 hour static test according to OECD 202 and EU method C.2. The test was performed with concentrations of 6.25, 12.5, 25, 50 and 100 mg test item/L(referring to 2.6, 5.2, 10.4, 20.8 and 41.5 mg solid content/L) and a blank control. Four replicates with 5 daphnids each were set up. After 48 hours 0, 0, 0. 0, 65 and 100 % immobilization was observed in the control and at test concentrations of 2.6, 5.2, 10.4, 20.8 and 41.5 mg solid content/L, respectively. Analytical measurements confirmed that the test solutions were correctly dosed and stable throughout the exposure period. Therefore the data were evaluated based on nominal concentrations. The EC50 is 19 mg solid content/L, the NOEC is 10.4 mg solid content/L.

The results are considered relevant and reliable for the risk assessment.