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Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data taken from peer reviewed database

Data source

Reference
Reference Type:
secondary source
Title:
J Pharm Sci 79
Author:
Kril MB, Fung HL
Year:
1990
Bibliographic source:
:440-443 (1990), cited in HSDB online query 19 March 2012

Materials and methods

Test guideline
Guideline:
other: measured
GLP compliance:
not specified
Type of method:
other: no datqa
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Pseudoephedrine
EC Number:
202-018-6
EC Name:
Pseudoephedrine
Cas Number:
90-82-4
Molecular formula:
C10H15NO
IUPAC Name:
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol
Details on test material:
name of test material (as cited in secondary source): Pseudoephidrine
Analytical purity: pure

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
0.89
Temp.:
25 °C

Any other information on results incl. tables

Value from generally accepted authoritative secondary source. No data available for pH.

Applicant's summary and conclusion