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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data taken from peer reviewed database

Data source

Reference
Reference Type:
secondary source
Title:
J Pharm Sci 79
Author:
Kril MB, Fung HL
Year:
1990
Bibliographic source:
:440-443 (1990), cited in HSDB online query 19 March 2012

Materials and methods

Test guideline
Guideline:
other: measured
GLP compliance:
not specified
Type of method:
other: no datqa
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Pseudoephedrine
EC Number:
202-018-6
EC Name:
Pseudoephedrine
Cas Number:
90-82-4
Molecular formula:
C10H15NO
IUPAC Name:
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol
Details on test material:
name of test material (as cited in secondary source): Pseudoephidrine
Analytical purity: pure

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
0.89
Temp.:
25 °C

Any other information on results incl. tables

Value from generally accepted authoritative secondary source. No data available for pH.

Applicant's summary and conclusion