Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: by loss of weight or by trapping vaporisate

Test material

Constituent 1
Chemical structure
Reference substance name:
Pseudoephedrine
EC Number:
202-018-6
EC Name:
Pseudoephedrine
Cas Number:
90-82-4
Molecular formula:
C10H15NO
IUPAC Name:
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol
Test material form:
solid: crystalline
Details on test material:
- Name of test material (as cited in study report): ( + )-Pseudoephedrine
- Physical state: solid
- Analytical purity: 99.9 %
- Lot/batch No.: 023513AX20

Results and discussion

Vapour pressureopen allclose all
Temp.:
20 °C
Vapour pressure:
0 hPa
Remarks on result:
other: extrapolated
Temp.:
25 °C
Vapour pressure:
0 hPa
Temp.:
50 °C
Vapour pressure:
0.008

Any other information on results incl. tables

Measured values:

      Temperature  Vapourpressure,p/hPa

          t/°C                     Cell1                  Cell3

25.1            3.29·10 -4                3.43·10-4

25.2             3.17·10 -4               3.17·10-4

34.7             1.20·10-3                1.25·10 -3

50.8             8.82·10 -3                9.04·10 -3

 

Applicant's summary and conclusion