Registration Dossier
Registration Dossier
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EC number: 603-373-3 | CAS number: 129909-90-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
ACZ is not a skin sensitiser nor a skin irritant.
Migrated from Short description of key information:
7.4.1 Skin sensitisation:
KS - GP. Zorbas, 1995. KL.1. Non-sensitiser
7.4.2 Respiratory sensitisation:
Data waiver
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
No studies are available which assess pulmonary function in animals or humans following repeated exposure. There is insufficient evidence to conclude that ACZ causes respiratory irritation, furthermore no evidence of sensitisation of the respiratory tract has been reported. The chemical structure does not contain a diisocynate group or other structural alerts (i. e. acid anhydride, platinum salt).
Migrated from Short description of key information:
7.4.2 Respiratory sensitisation: Waiver
Justification for classification or non-classification
Confirmed non-skin sensitiser. No evidence of potential sensitisation to the respiratory tract.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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