Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 243-296-9 | CAS number: 19780-11-1
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Aqueous abiotic hydrolysis would be expected to contribute significantly to the degradation of n-DDSA at pH 7.0 under the conditions associated with typical use and/or exposure in the environment. At pH 7.0, half-lives were determined to be 76 min. at 15 ºC , 35 min. at 25 ºC and 14 minutes at 35 ºC.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 35 min
- at the temperature of:
- 25 °C
Additional information
In the study entitled “n-DDSA Determination of the Abiotic Degradation of the Test Substance by Hydrolysis at Three Different pH Values Following OECD Guideline 111, The Official Journal of the European Communities L 142/518 Method C.7 and OPPTS Guideline 835.2120 and the Estimation of Water Solubility” a preliminary Tier 1 study was not conducted since n-DDSA is known to be hydrolytically unstable at pH 7.0. A Tier 2 test was conducted following OECD Guideline 111. At pH 7.0, half-lives were determined to be 76, 35 and 14 minutes at 15 ºC, 25 ºC and 35 ºC, respectively. The calculated half-life based on the Arrhenius Equation at 25 ºC was 33 minutes at pH 7.0. Based on these results, aqueous abiotic hydrolysis would be expected to contribute significantly to the degradation of the test substance at pH 7.0 under the conditions associated with typical use and/or exposure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
