3-(2-dodecenyl)succinic anhydride

Endpoint summary

Additional information

Short-term aquatic toxicity testing on tetrapropenyl succinic anhydride (CASRN 26544-38-7) was conducted in fish (Oncorhynchus mykiss), by read-across based on a grouping of substances (category approach). Short-term aquatic toxicity testing in aquatic invertebrates (Daphnia magna) was conducted on tripropenyl succinic acid (CASRN 147384-84-7), by read-across based on a grouping of substances (category approach).  An algal growth inhibition assay (Selenastrum capricornutum, now called Pseudokirchneriella subcapitata) and an activated sludge respiration inhibition assay were conducted on tetrapropenyl succinic anhydride (CASRN 26544-38-7), by read-across based on a grouping of substances (category approach). The 48-h EC₅₀ in daphnids and the 96-h LC₅₀ (loading rate) in fish were each reported at > 100 mg/L; the ErC₅₀ in algae was reported at a loading rate of 110 mg/L.  Long-term testing in fish and invertebrates was not conducted; the substance is rapidly hydrolysed in water at environmentally relevant temperature and pH conditions; the results of the chemical safety assessment showed that the risk characterization ratios for surface water are all below one.  Therefore, long-term aquatic toxicity testing was not indicated.