Registration Dossier
Registration Dossier
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EC number: 233-466-0 | CAS number: 10191-41-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Read across data are available for DL-Alpha-Tocopheryl acetate, a precursor of the substance. The respiration rate of microorganisms in presence of DL-Alpha-Tocopheryl acetate was tested by a oxygen consumption test according to ROBRA focusing on the respiration of Pseudomonas putida. After 30 minutes an EC50 > 10000 mg/l was determined (BASF AG, 1991).
Key value for chemical safety assessment
- EC50 for microorganisms:
- 10 000 mg/L
Additional information
Read across data are available for DL-Alpha-Tocopheryl acetate, a precursor of the substance. The respiration rate of microorganisms in presence of DL-Alpha-Tocopheryl acetate was tested by a oxygen consumption test according to ROBRA focusing on the respiration of Pseudomonas putida. After 30 minutes an EC50 > 10000 mg/l was determined (BASF AG, 1991).
In another test changes in the respiration rate of activated sludge as induced by DL-Alpha-Tocopheryl acetate were studied in a test performed in compliance with ISO 8192. An EC20 > 927 mg/l was determined after an inoculation time of 30 minutes.
As EC50 values are used as the basis for the calculation of a PNECstp, the study with Pseudomonas putida (BASF AG, 1991) is selected as key study.
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