Registration Dossier
Registration Dossier
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EC number: 219-251-4 | CAS number: 2396-61-4
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- 1. SOFTWARE
EPI Suite Vers. 4.11
2. MODEL (incl. version number)
ECOSAR Vers. 1.11
3. SMILES OR OTHER IDENTIFIERS USED AS INPUT FOR THE MODEL
CAS-No.: 2396-61-4
Smiles: O(CCCO)CCCO
4. SCIENTIFIC VALIDITY OF THE (Q)SAR MODEL
The documentation of the QSAR Models are available via the help function of the Software. The training and validity sets are
available at http://esc.syrres.com/interkow/EpiSuiteData.htm.
Similar substances such as several propanols and aliphatic alcoholes are included in the training sets. Similar substances are e.g.
2-Ethoxyethanol, Ethandiol, n-Propanol and 1,3-Propandiol.
Data source
Reference
- Reference Type:
- publication
- Title:
- EPISUITE 4.11 ECOSAR
- Year:
- 2 012
- Bibliographic source:
- US EPA 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: REACH Guidance on QSARs R.6
Test material
- Reference substance name:
- 3,3'-oxydipropanol
- EC Number:
- 219-251-4
- EC Name:
- 3,3'-oxydipropanol
- Cas Number:
- 2396-61-4
- Molecular formula:
- C6H14O3
- IUPAC Name:
- 3-(3-hydroxypropoxy)propan-1-ol
- Test material form:
- liquid
Constituent 1
Results and discussion
Effect concentrations
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 8 599 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- not specified
- Remarks on result:
- other: QSAR Predicted Value
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
