Registration Dossier
Registration Dossier
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EC number: 219-251-4 | CAS number: 2396-61-4
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Justification for type of information:
- The substance in this study is a mixture of isomers of the registered substance 3,3'-Oxydipropanol.
Data source
Reference
- Reference Type:
- publication
- Title:
- Dipropylene Glycol
- Year:
- 2 001
- Bibliographic source:
- OECD; SIDS Initial Assessment Report for Dipropylene Glycol, 25265-71-8 (2001). Available from, as of Febr 14, 2019: http://www.inchem.org/documents/sids/sids/25265-71-8.pdf
Materials and methods
Test guideline
- Guideline:
- other: No details on method reported
- GLP compliance:
- not specified
- Test type:
- acute toxic class method
- Limit test:
- no
Test material
- Reference substance name:
- Oxydipropanol
- EC Number:
- 246-770-3
- EC Name:
- Oxydipropanol
- Cas Number:
- 25265-71-8
- Molecular formula:
- C6H14O3
- IUPAC Name:
- 1,1'-oxydipropan-1-ol
- Reference substance name:
- 1,1'-oxydipropan-2-ol
- EC Number:
- 203-821-4
- EC Name:
- 1,1'-oxydipropan-2-ol
- Cas Number:
- 110-98-5
- Molecular formula:
- C6H14O3
- IUPAC Name:
- 1,1'-oxydipropan-2-ol
- Test material form:
- liquid
Constituent 1
Constituent 2
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- ca. 16 000 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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