Registration Dossier
Registration Dossier
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EC number: 233-279-4 | CAS number: 10102-90-6
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
The water solubility of the test material has been determined to be 9.00 x 10^-3 g/L of solution at 20.0 ± 0.5 °C.
Key value for chemical safety assessment
- Water solubility:
- 9 mg/L
- at the temperature of:
- 20 °C
Additional information
One study was performed in accordance with an accepted method (EU Method A.6) and under the conditions of GLP. This study is considered to be appropriate and reliable for use as a key study in accordance with Regulation (EC) No. 1907/2006 (REACH). No further testing is required.
Method
The determination was carried out by visual assessment using a flask method, based on Method A6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008.
Conclusion
The water solubility of the test material has been determined to be 9.00 x 10^-3 g/L of solution at 20.0 ± 0.5 °C.
The effect of temperature over the range 10 to 30 °C has been considered not to have had a significant influence on the solubility of the test material (range 8.18 x 10^-3to 9.00 x 10^-3 g/L).
The initial solution pH was shown to significantly influence solubility of the test material. When using an identical initial saturation period of 72 hours, the use of the pH 4 buffer solution significantly increased the resulting equivalent test material concentration dissolved (when compared to unbuffered water) to 0.266 g/L at 20.0 ± 0.5 °C (at a final solution pH of 3.8), whereas the use of the pH 9 buffer solution increased the resulting equivalent test material concentration to 0.295 g/L at 20.0 ± 0.5 °C (at a final solution pH of 6.7). Therefore, although the maximum observed solubility was 0.295 g/L (at a final solution pH of 6.7), the water solubility of the test material may increase further in cases where additional buffering capacity exists.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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