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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

Short description of key information on absorption rate using the closely related substance MEA polyborate (EC 247-421-8): 
Rat, mouse, rabbit and human skin were administered nominal doses of 4 mg/cm² of undiluted or aqueous MEA in vitro.  Mean dermal absorption values after 6 hours were 5.98,16.92, 8.66 and 0.61% (undiluted MEA) and 1.32, 24.79, 1.87 and 1.11% (aqueous MEA), respectively for rat, mouse, rabbit and human skin. It is appropriate to utilise the highest dermal absorption value for human skin to be conservative in risk assessment. Therefore, a dermal absorption value of 1.11% in aqueous MEA has been identified for human skin.

Key value for chemical safety assessment

Absorption rate - dermal (%):

Additional information