Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

The possible allergenic activity of slags, ferrous metal, blast furnace (air cooled - ABS), granular (8-11 mm) was tested according to OECD 406 and NF EN ISO 10993-10 (February 2003) concerning biological evaluation of medical devices: Tests for irritation and delayed-type hypersensitivity.Slag leachate was prepared by DIN 38414 -4 DEV S-4 by leaching for 24 h at a liquid/solid ratio of 10/1. For indcution, 21 Guinea pigs were exposed to the leachate in triplicate topical applications under occlusive dressing for 6 h, at 100%. After a 14-day rest phase, the challenge phase consisted of a single topical application (24 h) of the leachate at 100% and 50% dilution in demineralised water. No visible cutaneous reactions and no intolerance reaction were recorded in the challenge phase neither at 100% nor at 50%, and no reaction was recorded in the negative controls.Slag, ferrous metal, blast furnace is not irritating and does not need to be classified as a skin sensitiser. No signal word and no hazard statement are required.


Migrated from Short description of key information:
Slags, ferrous metal, blast furnace (air cooled – ABS) are not sensitizing when tested according to OECD 406 and NF EN ISO 10993-10 (February 2003) concerning biological evaluation of medical devices: Tests for irritation and delayed-type hypersensitivity.

Respiratory sensitisation

Endpoint conclusion
Additional information:

There is no indication of any sensitizing effect of ferrous slag.


Migrated from Short description of key information:
No data available

Justification for classification or non-classification

There is no skin sensitisation potential of slags, ferrous metal, blast furnace, as shown in a test according to OECD 406