Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Repeated dose toxicity: dermal

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Administrative data

Endpoint:
sub-chronic toxicity: dermal
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Justification for type of information:

For justification of read across see category justification attached to category object.

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(2-(2-ethoxyethoxy)ethoxy)ethanol
EC Number:
203-978-9
EC Name:
2-(2-(2-ethoxyethoxy)ethoxy)ethanol
Cas Number:
112-50-5
Molecular formula:
C8H18O4
IUPAC Name:
2-[2-(2-ethoxyethoxy)ethoxy]ethan-1-ol
Constituent 2
Reference substance name:
2-(2-(2-ethoxyyethoxy)ethoxy)ethanol
IUPAC Name:
2-(2-(2-ethoxyyethoxy)ethoxy)ethanol
Details on test material:
no data

Results and discussion

Effect levels

Dose descriptor:
NOAEL
Based on:
test mat.
Sex:
male/female
Remarks on result:
not determinable due to absence of adverse toxic effects
Remarks:
Based on a consideration of the results for this substance and other substances within the category, no adverse effects are expected for this substance when tested up to the limit dose of 1000 mg/kgbw/day.

Target system / organ toxicity

Critical effects observed:
no

Applicant's summary and conclusion