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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Pimephales Promelas: LC50(96hrs) >10000mg/l.

Carrassius auratus: LC50(24 hrs) >5000mg/l.

Danio rerio (Embryotoxicity test, 96hrs), NOEC>1780mg/L (for substance and main metabolite)

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
10 000 mg/L

Additional information

A limited number of acute toxicity studies are available in fish. These clearly show that the substance 2-(2-(2-ethoxyyethoxy)ethoxy)ethanol is practically non-toxic to fish. The LD50 was always in excess of the maximum tested dose. A figure of 10000mg/L is appropriate. The substance has also been tested in the zebrafish embryotoxicity test and showed neither it or its main metabolite 2 -(2 -(2 -ethoxyethoxy)ethoxy) acetic acid showed any toxicity up to the maximum tested dose of 10mM (1780mg/L).