Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Carcinogenicity

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Administrative data

Description of key information

A rodent carcinogenicity study for Vinyl 2-ethylhexanoate is not needed as established by the criteria set out in REACH Annex X, Column 2.  

Key value for chemical safety assessment

Justification for classification or non-classification

Vinyl 2 -ethylhexanoate dose not meet the criteria for Classification and Labeling as a Carcinogen as established by EU Directive 67/548/EEC and the CLP.

Additional information

Vinyl 2 -ethylhexanoate is not genotoxic in four in vitro assays and in one in vivo rat study for DNA and chromosome damage. Therefore, the criteria for a Category 3 mutagen are not met. Vinyl 2 -ethylhexanoate is manufactured under closed conditions with little or no environmental release or worker or consumer exposure. In repeated-dose rodent studies Vinyl 2 -ethylhexanoate did not induce human health relevant histopathology.