Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-924-1
CAS number: 101-20-2
To evaluate the effect of test
chemical on the domestic sewage by providing the exposure period of 16
days. Domestic sewage was obtain ocean County South Treatment Plant
Test. Anaerobic Digester Inhibition test was performed. After the
exposure period of 16 days, effect of test chemical on the domestic
sewage were determine. The NOEC was determine to be at 100 mg/l.
Toxicity to microorganisms:
The MIC values were determined by the
microbroth dilution assay according to the National Committee for
Clinical Laboratory Standards methods for antimicrobial susceptibility
tests for aerobically growing bacteria (Approved Standard M7-A2, NCCLS,
Villanova, PA, 1990).
Approximately 6.5 3 108 cells of strain
RN4220 (25) were plated on to brain-heart infusion agar medium
(Becton-Dickinson) containing 0.5 mg/ml test material. The plates were
incubated at 37 °C with periodic monitoring. After 48 h, resistant
clones were picked and their phenotype confirmed by regrowth on the
original selective concentration of test material.
Three strains of Staphylococcus aureus
namely RN4220 (wild-type) , RN4220/pTri-1 , GR664 (fabIG23S) and three
starins of E.coli
W3110 (wild-type) , W3110/pFabI , RJH108
(fabIG93V) . The wild-type FabI proteins from either S. aureus or E.
coli were expressed using plasmids pTri-1 or pFabI, respectively, to
determine if resistance was conferred by the presence of multiple copies
of the fabI genes.
The minimum ihhibition concentration (MIC)
was observed in the range of 0.25 to 2 mg/l in case of Staphylococcus
aureus and for E.Coli MIC was observed in concentration range of 0.5 -
In another secondary data for test chemical
the effect of test chemical on the domestic sewage by providing the
exposure period of 16 days. Domestic sewage was obtain ocean County
South Treatment Plant Test. Anaerobic Digester Inhibition test was
performed. After the exposure period of 16 days, effect of test chemical
on the domestic sewage were determine. The NOEC was determine to be at
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again